Effect of ethanol on rat-liver ribonucleoprotein previously exposed to cold trichloroacetic acid

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Effect of ethanol on ratliver ribonucleoprotein previously exposed to cold trichloroacetic acid.

The separation of liver ribonucleic acid and deoxyribonucleic acid from the associated protein material without hydrolysis can be accomplished by a salt-extraction procedure described by Barnum & Huseby (1950). This method, based on ribose recovery (Lowe & Rand, 1956; C. U. Lowe & P. R. Venkataraman, in preparation), yields 80% of the total ribonucleic acid of normal liver homogenate or cell fr...

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Effect of exposure to cold on pantothenic acid metabolism in rat liver.

Exposure to a cold environment increased the incorporation of labeled pantothenic acid (PaA) into the liver and total PaA content. These increases were mainly due to an increase of free coenzyme A (CoA). The specific activity of the free CoA fraction was particularly high. These results suggest that exposure to a cold environment accelerates the rate of synthesis of CoA from PaA in the liver.

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Testicular changes in rat exposed to Trichloroacetic Acid (TCA) during organogenesis

Halogenated hydrocarbons such as Trichloroacetic acid (TCA) are among the most common water supply contaminants in the world. The study was, therefore undertaken to examine the effect of Trichloroacetic acid on the developing testis of Charles foster rat. The rats were randomly placed in the test groups and exposed to various concentrations of TCA i.e. 1000,1200,1400,1600 and 1800 mg/Kg body we...

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Trichloroacetic acid effects on rat liver peroxisomes and enzyme-altered foci.

The initiating and promoting effects of trichloroacetic acid (TCA) were investigated using a rat hepatic enzyme-altered foci bioassay. The experimental protocol used has been shown to induce gamma-glutamyltranspeptidase (GGT)-positive foci in hepatic tissue following an initiating dose with a genotoxic carcinogen. Twenty-four hours following 2/3 partial hepatectomy, rats received either a singl...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1959

ISSN: 0306-3283

DOI: 10.1042/bj0720430